Author

Anoop Misra*, MD; Seema Gulati*, PhD

Result

MUFA-rich diet improved insulin sensitivity, as indicated by lower HOMA-IR values post-intervention, compared with carbohydrate-rich and high-saturated fat diets.

Results suggest significant improvements in grading of fatty liver, liver span, measures of insulin resistance, and lipids with use of canola and olive oil compared with control oils in Asian Indians with NAFLD.

Conclusion

Conclusion we have shown that a daily supplementation of 50 grams of rapeseed/canola oil might be considered as a potential therapeutic tool and a favorable, easy to manage daily nutritional supplementation” for the treatment of liver steatosis, since a reduction of serum liver enzymes was achieved in obese

Author

Lan-Pidhainy X, Wolever TM

Result

MUFA-rich diet improved insulin sensitivity, as indicated by lower HOMA-IR values post-intervention, compared with carbohydrate-rich and high-saturated fat diets.

Results suggest significant improvements in grading of fatty liver, liver span, measures of insulin resistance, and lipids with use of canola and olive oil compared with control oils in Asian Indians with NAFLD.

Conclusion

The hypoglycemic effect of fat (Canola oil) and protein was not blunted by insulin resistance. Protein increased insulin but had no effect on C-peptide or the insulin secretion rate, which suggests decreased hepatic insulin extraction or increased C-peptide clearance.

Author

Michael Kruse1,2, Christian von Loeffelholz1,2,3,4, Daniela Hoffmann1, Antje Pohlmann1, Anne-Cathrin Seltmann1, Martin Osterhoff1,2, Silke Hornemann1,2, Olga Pivovarova1, Sascha Rohn5, Gerhard Jahreis6 and Andreas F. H. Pfeiffer1,2

Result

A significant increase of ALA and also of EPA, which probably was a result of ALA elongation [33], in serum of participants in the RA (Rapeseed oil) group, but not in the OL group, indicating a high adherence to oil consumption (Fig. 2). DHA, which is also a conversion product of ALA, however was not changed in both groups

Conclusion

We could see improved insulin sensitivity determined by the HOMA IR index despite an increase in energy from fat above 40% after oil consumption for RA and OL that, however, was statistically significant for RA